Searchable abstracts of presentations at key conferences in endocrinology

ea0063gp71 | Thyroid Autoimmune Disorders | ECE2019

The randomised probiotic trial of indigo study (investigation of novel biomarkers and definition of role of the microbiome in Graves’ orbitopathy)

Salvi Mario , Colucci Giuseppe , Masetti Giulia , Covelli Danila , Muller Ilaria , Koehling Hedda , Garaiova Iveta , Michael Daryn , Zhang Lei , Ludgate Marian , Marchesi Julian , Biscarini Filippo

Background: Changes of the gut microbiota may impact on the mechanisms of immune tolerance in GravesÂ’ disease (GD) and GravesÂ’ orbitopathy (GO). Probiotics, which contain live micro-organisms, can modify the composition of the gut microbiota.Aims: We tested in a double-blind randomized placebo controlled trial whether the administration of a well-characterized, commercially available, probiotic would 1) modify the microbiota composition in GD/G...